Bayesian Graphical Models for Genomewide Association Studies
نویسندگان
چکیده
منابع مشابه
A Bayesian Graphical Model for Genome-wide Association Studies (GWAS)
The present paradigm to analyze GWAS is to perform an exhausting testing of all single SNP associations with the response variable with the major drawback that the selected subset of SNPs has in general a very low predictive value. As a shift to the usual approach, we propose here a general statistical framework for GWAS based on Bayesian graphical modeling and able to: 1) Assess the joint effe...
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ژورنال
عنوان ژورنال: The American Journal of Human Genetics
سال: 2006
ISSN: 0002-9297
DOI: 10.1086/505313